Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 4/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 3/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505593 | 0.92 | ADORA2A (0.35) | KDM4ECDC7DBF4HPGD | |
| SCHEMBL6504395 | 0.91 | PPARA (0.37) | CNR1CNR2MAPTWDR5KLKB1 | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.90 | SHMT1 (0.44) | SHMT1SHMT2CNR1CNR2KDM4E | |
| SCHEMBL6498709 | 0.88 | CDK2 (0.34) | MAPTWDR5KLKB1 | |
| SCHEMBL6531507 | 0.86 | PARP1 (0.36) | KDM4EMAPTHPGDKMT2A | |
| SCHEMBL6505045 | 0.86 | SMN1; SMN2 (0.35) | KDM4EHPGDKMT2A | |
| SCHEMBL6499174 | 0.85 | ADORA1 (0.38) | KDM4EMAPTHPGDWDR5KMT2A | |
| SCHEMBL6505057 | 0.85 | HPGD (0.48) | HPGDKLKB1EPHX2KMT2A | |
| SCHEMBL6494741 | 0.84 | PPARA (0.39) | MAPTWDR5KMT2A | |
| SCHEMBL6503597 | 0.84 | KDM4E (0.36) | KDM4EMAPTKLKB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |