Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494848 | 0.83 | LMNA (0.36) | MAPTNOTUMPTPN5TNKSPARP1 | |
| SCHEMBL5797082 | 0.81 | MAOB (0.35) | MAPTTNKSPARP1TNKS2NPC1 | |
| SCHEMBL9128405 | 0.79 | TAAR1 (0.47) | MAPTGCGRMAPK14NPC1RAB9A | |
| SCHEMBL9648734 | 0.79 | ACHE (0.41) | MAPTNPC1RAB9AKDM4EHPGD | |
| SCHEMBL436469 | 0.79 | NOTUM (0.38) | NOTUMMAPK14NPC1RAB9ATP53 | |
| SCHEMBL8089002 | 0.79 | CASR (0.39) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL22463151 | 0.76 | AHR (0.46) | MAPTNOTUMNPC1RAB9ATP53 | |
| SCHEMBL10644670 | 0.76 | PTGS2 (0.37) | MAPTNOTUMTNKSPARP1TNKS2 | |
| SCHEMBL5736161 | 0.76 | PTPN5 (0.34) | NOTUMPTPN5TNKSPARP1TNKS2 | |
| SCHEMBL5796805 | 0.76 | ESR2 (0.47) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |