Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363389 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6499677 | 0.80 | UHRF1 (0.42) | — | |
| SCHEMBL6499767 | 0.77 | CYP3A4 (0.35) | ERN1SMN1; SMN2 | |
| SCHEMBL28135126 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL6501548 | 0.72 | CFTR (0.41) | SMN1; SMN2 | |
| SCHEMBL5899050 | 0.71 | NOS3 (0.46) | NOS3NOS2NOS1 | |
| SCHEMBL6499586 | 0.67 | PSEN1 (0.44) | ALDH1A1 | |
| SCHEMBL1100811 | 0.67 | ERN1 (0.39) | ERN1ALDH1A1 | |
| SCHEMBL9729373 | 0.67 | ACHE (0.46) | ALDH1A1 | |
| SCHEMBL7489 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | NOS3 108/4885NOS2 126/4885NOS1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.