Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505454 | 0.84 | ACACB (0.49) | MMP12 | |
| SCHEMBL6507161 | 0.81 | RARB (0.46) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL6505903 | 0.81 | MMP12 (0.64) | MMP12 | |
| SCHEMBL6503745 | 0.79 | THRA (0.46) | RARBRARAMEN1ALDH1A1MAPT | |
| SCHEMBL6527017 | 0.77 | MMP12 (0.40) | RARBRARAMMP12RARGMEN1 | |
| SCHEMBL8719496 | 0.76 | RARB (0.55) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL6505017 | 0.75 | MMP12 (0.51) | MMP12MEN1ALDH1A1KMT2A | |
| SCHEMBL237103 | 0.75 | PPARA (0.53) | RARBRARARARGMEN1ALDH1A1 | |
| Bicarbonate SCHEMBL27570637 | 0.74 | PPARA (0.57) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL8721451 | 0.74 | RARB (0.58) | RARBRARARARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |