Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503746 | 0.80 | THRA (0.46) | THRATHRBRARBHSD17B3MEN1 | |
| SCHEMBL6507158 | 0.79 | RARB (0.45) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL6505903 | 0.79 | MMP12 (0.64) | — | |
| SCHEMBL9138023 | 0.77 | THRA (0.72) | THRATHRBRARBHSD17B3MEN1 | |
| SCHEMBL6505454 | 0.76 | ACACB (0.49) | — | |
| SCHEMBL10778455 | 0.75 | RARB (0.71) | THRATHRBRARBHSD17B3MEN1 | |
| SCHEMBL6506346 | 0.73 | KMT2A (0.43) | MEN1MAPTKMT2A | |
| SCHEMBL6505017 | 0.72 | MMP12 (0.51) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8501592 | 0.72 | THRA (0.57) | THRATHRBHSD17B3 | |
| SCHEMBL4293988 | 0.72 | THRA (0.57) | THRATHRBHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |