Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504564 | 0.90 | HTR6 (0.54) | MAPTLMNAL3MBTL1HTR6DRD2 | |
| SCHEMBL6501509 | 0.88 | HTR6 (0.46) | MAPTLMNAHTR6DRD2HTR2A | |
| SCHEMBL6506073 | 0.88 | LMNA (0.44) | MAPTLMNAHTR7L3MBTL1HTR6 | |
| SCHEMBL6500880 | 0.87 | LMNA (0.51) | MAPTLMNAHTR7L3MBTL1HTR6 | |
| SCHEMBL6510748 | 0.87 | HTR6 (0.46) | HTR6DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL6502583 | 0.87 | LMNA (0.48) | MAPTLMNAL3MBTL1HTR6DRD2 | |
| SCHEMBL6509242 | 0.86 | MAOB (0.54) | MAPTLMNAHTR7HTR6HTR2A | |
| SCHEMBL6507562 | 0.85 | MAPT (0.57) | MAPTLMNAHTR7L3MBTL1HTR6 | |
| SCHEMBL6501982 | 0.85 | DRD2 (0.47) | MAPTLMNAL3MBTL1HTR6DRD2 | |
| Hydrochloric Acid SCHEMBL6504357 | 0.85 | MAOB (0.53) | MAPTLMNAHTR7HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |