Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500880 | 0.91 | LMNA (0.51) | MAPTHTR6L3MBTL1HTR7POLB | |
| SCHEMBL6502583 | 0.91 | LMNA (0.48) | MAPTHTR6L3MBTL1POLBALDH1A1 | |
| SCHEMBL6501509 | 0.91 | HTR6 (0.46) | MAPTHTR6POLBKMT2AALDH1A1 | |
| SCHEMBL6510748 | 0.87 | HTR6 (0.46) | HTR6POLBKMT2AALDH1A1HPGD | |
| SCHEMBL6509242 | 0.86 | MAOB (0.54) | MAPTHTR6HTR7KMT2ALMNA | |
| SCHEMBL6504564 | 0.86 | HTR6 (0.54) | MAPTHTR6L3MBTL1DRD2LMNA | |
| SCHEMBL6511504 | 0.85 | DRD2 (0.52) | MAPTL3MBTL1POLBMMP2MMP13 | |
| SCHEMBL6508620 | 0.85 | MAPT (0.49) | MAPTHTR6L3MBTL1HTR7DRD2 | |
| Hydrochloric Acid SCHEMBL6504357 | 0.85 | MAOB (0.53) | MAPTHTR6HTR7KMT2ALMNA | |
| SCHEMBL6506073 | 0.83 | LMNA (0.44) | MAPTHTR6L3MBTL1HTR7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |