Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509679 | 0.93 | SMN1; SMN2 (0.45) | PTPN1HTTTDP1SMN1; SMN2HDAC3 | |
| SCHEMBL6510335 | 0.86 | HTT (0.43) | PTPN1HTTTDP1HDAC3HDAC1 | |
| SCHEMBL6511657 | 0.85 | HDAC3 (0.50) | PTPN1HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL6514104 | 0.84 | KMT2A (0.42) | PTPN1HTTTDP1HDAC3HDAC1 | |
| SCHEMBL6511151 | 0.84 | RAB9A (0.43) | PTPN1HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL6510153 | 0.84 | PKM (0.47) | HTTHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6511663 | 0.83 | HTT (0.43) | PTPN1HTTSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6515044 | 0.83 | ALDH1A1 (0.41) | PTPN1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6511947 | 0.80 | MTNR1A (0.47) | PTPN1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6519103 | 0.79 | KMT2A (0.50) | HTTHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |