Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6521244

N.O=S(=O)(O)OOS(=O)(=O)O.O=S(=O)([O-])OOS(=O)(=O)[O-].[Na+].[Na+]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 1/20 0.59
TSHR P16473 3/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.32
RECQL P46063 2/20 0.30
GLA P06280 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
EPHX2 P34913 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28092733 1.00 CA2 (0.59) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL6744600 1.00 CA2 (0.59) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL2446143 1.00 CA2 (0.59) CA2TSHRMEN1ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL28030523 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL27834069 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Sulfuric Acid SCHEMBL20280977 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL28259468 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL10277725 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL21383094 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL28259653 0.97 CA2 (0.56) CA2TSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088651-A1 ETHYLENE/TETRAFLUOROETHYLENE COPOLYMER, METHOD FOR ITS PRODUCTION, POWDER COATING MATERIAL AND MOLDED ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2017-03-30 US disclosed
EP-0789047-B1 WATER ABSORPTIVE RESIN COMPOSITION AND METHOD OF MANUFACTURING THE SAME NIPPON CATALYTIC CHEM IND (JP) 2005-12-21 EP disclosed
EP-1394622-A2 Toner and image forming apparatus using the same SEIKO EPSON CORPORATION (JP) 2004-03-03 EP disclosed
US-6133193-A ABSORBENT RESIN OF SPECIFIC PARTICLE SIZE TOGETHER WITH POLYHYDRIC ALOCHOL, AN AMINO GROUP COMPOUND, AN AMIDE COMPOUND AND CARBOXY CONTAINING COMPOUND USED FOR SANITARY NAPKINS, DISPOSABLE DIAPERS, AGRICULTURE AND HORTICULTURE NIPPON SHOKUBAI CO., LTD. (JP) 2000-10-17 US disclosed
EP-0789047-A1 WATER ABSORPTIVE RESIN COMPOSITION AND METHOD OF MANUFACTURING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 1997-08-13 EP disclosed