Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24181312 | 0.89 | PARP10 (0.46) | CYP2A6ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7670360 | 0.80 | ESR1 (0.38) | ALDH1A1 | |
| SCHEMBL13437662 | 0.79 | PANK3 (0.33) | — | |
| SCHEMBL16903598 | 0.78 | CYP2A6 (0.38) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL2646831 | 0.77 | ESR1 (0.52) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL3026921 | 0.77 | HSD17B10 (0.46) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL7141602 | 0.75 | MAOA (0.45) | CYP2A6ALDH1A1SMN1; SMN2RAB9APOLB | |
| SCHEMBL3976211 | 0.75 | CYP2A6 (0.52) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL6947258 | 0.74 | ALDH5A1 (0.43) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL24628752 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518166-A | Peptide-like compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-105873925-B | Antiparasitic and insecticidal isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2019-09-10 | — | — | CN | disclosed |
| US-9955689-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-01 | — | — | US | disclosed |
| US-9894901-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9872493-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-23 | — | — | US | disclosed |
| CN-106748638-A | A kind of preparation method of trifluoroethyl substituted arene compound | 四川理工学院 | 2017-05-31 | — | — | CN | disclosed |
| CN-105873925-A | Antiparasitic and insecticidal isoxazoline compounds | 梅里亚股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20150305332-A1 | METHOD FOR PROMOTING PLANT GROWTH | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-29 | — | — | US | disclosed |
| US-20150289506-A1 | METHOD FOR PROMOTING PLANT GROWTH | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20150289512-A1 | METHOD FOR PROMOTING PLANT GROWTH | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-15 | — | — | US | disclosed |
| EP-2923573-A1 | METHOD FOR PROMOTING PLANT GROWTH | Sumitomo Chemical Company Limited (JP) | 2015-09-30 | — | — | EP | disclosed |
| EP-2923574-A1 | METHOD FOR PROMOTING PLANT GROWTH | Sumitomo Chemical Company Limited (JP) | 2015-09-30 | — | — | EP | disclosed |
| EP-1425015-A4 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1425015-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6593335-B1 | Disease than can be ameliorated with a potassium channel opener in a host mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of the compound of claim 1; said disease is epilepsy, Raynaud's | ABBOTT LABORATORIES | 2003-07-15 | — | — | US | disclosed |
| WO-2003015715-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| US-6512030-B2 | Plastic additives which are useful as nucleating agents and which are especially useful for improving the optical properties of polymeric materials such as polyolefins; also as gelling agents for antiperspirant gels | MILLIKEN & COMPANY | 2003-01-28 | — | — | US | disclosed |
| US-20020193473-A1 | Novel asymmetric monofluorinated benzaldehyde alditol derivatives and compositions and articles containing same | MILLIKEN & COMPANY | 2002-12-19 | — | — | US | disclosed |
| EP-1194429-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078768-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150289506-A1 | METHOD FOR PROMOTING PLANT GROWTH | FGF2, BROX, BOLA2; BOLA2B | CYP2A6 623/4885HSD17B10 199/4885ALDH5A1 777/4885 |
| US-20150305332-A1 | METHOD FOR PROMOTING PLANT GROWTH | FGF1, BROX, FGF2 | CYP2A6 1195/4885HSD17B10 1052/4885ALDH5A1 2077/4885 |
| US-20020193473-A1 | Novel asymmetric monofluorinated benzaldehyde alditol derivatives and compositions and articles containing same | DERA, ALDOA, SORD | CYP2A6 3577/4885HSD17B10 1269/4885ALDH5A1 376/4885 |
| US-20150289512-A1 | METHOD FOR PROMOTING PLANT GROWTH | FGF1, MKI67, FGF2 | CYP2A6 1797/4885HSD17B10 432/4885ALDH5A1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.