Thiosulfuric Acid

Thiosulfuric Acid

SCHEMBL6546202

O=S(O)(O)=S.O=S([O-])([O-])=S.[Na+].[Na+]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 1/20 0.33
CA2 known ✓ P00918 1/20 0.33
CA4 known ✓ P22748 1/20 0.33
TSHR P16473 3/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 1/20 0.61
KMT2A Q03164 1/20 0.61
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
NT5E P21589 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiosulfuric Acid SCHEMBL3721921 1.00 TSHR (0.61) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL8459656 0.96 TSHR (0.57) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL2818447 0.96 TSHR (0.57) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL28293103 0.93 MEN1 (0.53) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL10958542 0.92 TSHR (0.61) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL1232606 0.92 TSHR (0.61) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL3422846 0.92 TSHR (0.61) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL26087399 0.92 TSHR (0.61) TSHRMEN1ALDH1A1KMT2ACA5A
Sulfuric Acid SCHEMBL3859535 0.92 TSHR (0.75) TSHRMEN1ALDH1A1KMT2ACA5A
Thiosulfuric Acid SCHEMBL17165012 0.92 TSHR (0.50) TSHRMEN1ALDH1A1KMT2ACA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135651-A Substituted nucleoside analogs as PRMT5 inhibitors 鲁皮恩有限公司 2022-09-30 CN disclosed
CN-212740802-U Intelligent control system based on coking desulfurization waste liquid colour 中钢集团鞍山热能研究院有限公司 2021-03-19 CN disclosed
CN-111847569-A Intelligent control system based on coking desulfurization waste liquid colour 中钢集团鞍山热能研究院有限公司 2020-10-30 CN disclosed
CN-106866267-A A kind of pre-buried fertilizing method of loquat special fertilizer in suitable Jiangsu and Zhejiang Provinces area 苏州梦龙文化旅游发展有限公司 2017-06-20 CN disclosed
US-8436105-B2 Vulcanizable composition having acoustic attenuating properties HENKEL AG & CO. KGAA (DE) 2013-05-07 US disclosed
US-20120136129-A1 VULCANIZABLE COMPOSITION HAVING ACOUSTIC ATTENTUATING PROPERTIES HENKEL AG & CO., KGAA (DE) 2012-05-31 US disclosed
EP-0980022-B1 Method for preparing silver halide emulsion and silver halide photographic material KONISHIROKU PHOTO IND (JP) 2004-05-06 EP disclosed
EP-0711592-B1 Method of manufacturing solid processing composition for silver halide photographic light-sensitive materials KONISHIROKU PHOTO IND (JP) 2004-01-21 EP disclosed
EP-0838721-B1 Processing method of silver halide light sensitive photo graphic material KONISHIROKU PHOTO IND (JP) 2003-09-10 EP disclosed
US-6524782-B1 No roller mark even during rapid processing at low replenish rates; no stain due to remained sensitizing dye; reacting silver salt and a halide salt in presence of fine silver halide grains containing gallium, indium and Group 8, 9, 10 KONICA CORPORATION (JP) 2003-02-25 US disclosed
EP-0768568-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1997-04-16 EP disclosed
EP-0762192-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1997-03-12 EP disclosed
US-5568221-A Apparatus for processing silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1996-10-22 US disclosed
EP-0711592-A2 Method of manufacturing solid processing composition for silver halide photographic light-sensitive materials KONICA CORPORATION (JP) 1996-05-15 EP disclosed
EP-0712038-A2 Processing method of silver halide photographic light sensitive material KONICA CORPORATION (JP) 1996-05-15 EP disclosed
EP-0706087-A1 Method for processing silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1996-04-10 EP disclosed
EP-0704756-A1 Photographic processing method for processing a silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1996-04-03 EP disclosed
EP-0699957-A1 Light-sensitive silver halide photographic material processing apparatus KONICA CORPORATION (JP) 1996-03-06 EP disclosed
US-4417012-A DIENE RUBBER MONSANTO EUROPE S.A. (BE) 1983-11-22 US disclosed
EP-0070143-A1 Organic thiosulphates and thiosulphonates useful as stabilising agents for rubber vulcanisates MONSANTO EUROPE S.A./N.V. (BE) 1983-01-19 EP disclosed