Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL3721921 | 0.96 | TSHR (0.61) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL6546202 | 0.96 | TSHR (0.61) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL2420407 | 0.92 | TSHR (0.47) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL7615104 | 0.92 | TSHR (0.57) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL2818447 | 0.92 | TSHR (0.57) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL28293103 | 0.89 | MEN1 (0.53) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL17165012 | 0.88 | TSHR (0.50) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL3859535 | 0.88 | TSHR (0.75) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Thiosulfuric Acid SCHEMBL10958542 | 0.88 | TSHR (0.61) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL1232606 | 0.88 | TSHR (0.61) | TSHRMEN1ALDH1A1KMT2ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658612-B1 | Polysaccharide containing fluids having enhanced thermal stability | TEXAS UNITED CHEMICAL CORP (US) | 1999-05-26 | — | — | EP | claimed |
| EP-0401846-A2 | A direct positive silver halide photographic light-sensitive material and a processing method therefor | KONICA CORPORATION (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4952488-A | DESILVERING ACCELERATOR, ARYLUREIDO AND CARBOXAMIDO SUBSTITUTED PHENOLIC CYAN COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |