Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 7/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317367 | 0.88 | ALDH1A1 (0.53) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL27934597 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL11472938 | 0.83 | ATM (0.57) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1749934 | 0.82 | ALDH1A1 (0.57) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL13864204 | 0.81 | ABCB11 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2CA1 | |
| SCHEMBL566413 | 0.81 | NPC1 (0.62) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL9439348 | 0.81 | ALDH1A1 (0.69) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL45113 | 0.81 | MRGPRX4 (0.57) | ALDH1A1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL4739829 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7055711 | 0.80 | IDO1 (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034020-A1 | Methods of treating periodontal disease | DALUGE SUSAN MARY (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1104422-B1 | PHENYL XANTHINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-02-18 | — | — | EP | disclosed |
| US-20030032804-A1 | Methods of treating periodontal disease | SMITHKLINE BEECHAM CORPORATION | 2003-02-13 | — | — | US | disclosed |
| EP-1104422-A1 | PHENYL XANTHINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009507-A1 | PHENYL YANTHINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034020-A1 | Methods of treating periodontal disease | MMP8, LPO, PTGES3 | ALDH1A1 2314/4885NPC1 1548/4885POLB 1244/4885 |
| US-20030032804-A1 | Methods of treating periodontal disease | HPGDS, SELP, ALPI | ALDH1A1 2569/4885NPC1 1592/4885POLB 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.