Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558342 | 0.97 | SLC22A1 (0.55) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL9160986 | 0.95 | ALDH1A1 (0.57) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL302025 | 0.87 | DNM1 (0.50) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| SCHEMBL15536304 | 0.81 | SLC22A1 (0.56) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL25190911 | 0.81 | LMNA (0.64) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL2772679 | 0.80 | DNM1 (0.48) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8098887 | 0.80 | DNM1 (0.48) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4603559 | 0.80 | DNM1 (0.48) | SLC22A1DNM1ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL17200531 | 0.77 | DNM1 (0.56) | SLC22A1DNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL28550601 | 0.77 | DNM1 (0.56) | SLC22A1DNM1HTTPLA2G1BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165152-A1 | TEXTILE TREATMENT COMPOSITIONS | Enviro Specialty Chemicals Inc. (US) | 2023-04-19 | — | — | EP | claimed |
| US-20210395652-A1 | TEXTILE TREATMENT COMPOSITIONS | ANGRES, ISAAC A, PHD | 2021-12-23 | — | — | US | claimed |
| WO-2021253015-A1 | TEXTILE TREATMENT COMPOSITIONS | ENVIRO SPECIALTY CHEMICALS INC (US) | 2021-12-16 | — | — | WO | claimed |
| EP-0850934-B1 | Triazinylaminostilbene ultra-violet absorbing agents | CIBA SC HOLDING AG (CH) | 2004-03-10 | — | — | EP | claimed |
| EP-0659877-B1 | Composition for the treatment of textiles | CIBA SC HOLDING AG (CH) | 2003-06-04 | — | — | EP | claimed |
| US-6398982-B1 | FABRIC RINSE FORMULATION INCLUDING HYDROXYARYL 1,3,5-TRIAZINE OR SULFONATED BENZOTRIAZOLE UV ABSORBER; INCREASING SUN PROTECTION FACTOR OF CLOTHING | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | claimed |
| US-6174854-B1 | STABLE, AQUEOUS FABRIC SOFTENING RINSE CONCENTRATE COMPRISING AN ULTRAVIOLET LIGHT ABSORBING 2-N-(2-HYDROXY-3,5-DIALKYL-PHENYL)-2H-BENZOTRIAZOLE AND A TETRAALKYLAMMONIUM COMPOUND; STEROL-FREE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-01-16 | — | — | US | claimed |
| EP-0850934-A1 | Triazinylaminostilbene ultra-violet absorbing agents | Ciba SC Holding AG (CH) | 1998-07-01 | — | — | EP | claimed |
| US-5688758-A | CATIONIC, AMPHOTERIC, OR ANIONIC SURFACTANTS, FLUORESCENT WHITENING DYES AND FABRIC CARE COMPOUNDS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-18 | — | — | US | claimed |
| EP-0659877-A2 | Composition for the treatment of textiles | CIBA-GEIGY AG (CH) | 1995-06-28 | — | — | EP | claimed |
| US-4851141-A | HEXYLENE GLYCOL CARRIER LIQUID; QUATERNARY AMMONIUM, IMIDALIUM, OR PYRIMIDINIUM COMPOUNDS | COLGATE-PALMOLIVE COMPANY (US) | 1989-07-25 | — | — | US | claimed |
| EP-4165152-A1 | TEXTILE TREATMENT COMPOSITIONS | Enviro Specialty Chemicals Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| US-20210395652-A1 | TEXTILE TREATMENT COMPOSITIONS | ANGRES, ISAAC A, PHD | 2021-12-23 | — | — | US | disclosed |
| WO-2021253015-A1 | TEXTILE TREATMENT COMPOSITIONS | ENVIRO SPECIALTY CHEMICALS INC (US) | 2021-12-16 | — | — | WO | disclosed |
| EP-0682145-B1 | Textile treatment | CIBA SC HOLDING AG (CH) | 2004-08-25 | — | — | EP | disclosed |
| US-4851141-A | HEXYLENE GLYCOL CARRIER LIQUID; QUATERNARY AMMONIUM, IMIDALIUM, OR PYRIMIDINIUM COMPOUNDS | COLGATE-PALMOLIVE COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4844823-A | SYNERGISTIC MIXTURE WITH FATTY ALCOHOL | COLGATE-PALMOLIVE COMPANY (US) | 1989-07-04 | — | — | US | disclosed |
| US-4806260-A | Built nonaqueous liquid nonionic laundry detergent composition containing acid terminated nonionic surfactant and quarternary ammonium softener and method of use | COLGATE-PALMOLIVE COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4789496-A | ALKYLQUATERNARY AMMONIUM SURFALTANT | COLGATE-PALMOLIVE COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| US-4772403-A | QUATERNARY AMMONIUM COMPOUND, FATTY ALCOHOL | COLGATE PALMOLIVE COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395652-A1 | TEXTILE TREATMENT COMPOSITIONS | PPM1D, SMARCC2, REV1 | SLC22A1 4521/4885DNM1 939/4885ALDH1A1 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.