Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.62 |
| ▸ | HTR7 | P34969 | 8/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162084 | 0.86 | HTR1A (0.57) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL7591674 | 0.82 | ADRB1 (0.80) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL7055201 | 0.81 | HTR7 (0.57) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL7059249 | 0.80 | HTR3A (0.65) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL255197 | 0.78 | HTR3A (0.67) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL4909469 | 0.77 | HTR7 (0.58) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL6963568 | 0.77 | HTR6 (0.65) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL2209183 | 0.77 | ADRB1 (1.00) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL4896 | 0.77 | ADRB1 (1.00) | ADRB1HTR7HTR1AHTR3AHTR3E | |
| SCHEMBL29432760 | 0.77 | ADRB1 (1.00) | ADRB1HTR7HTR1AHTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138678-B1 | Process for making N-((4-phenyl) methylphenyl) piperazines | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1138678-A3 | Process for making N-((4-phenyl) methylphenyl) piperazines | SUNTORY LIMITED (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-1138678-A2 | Process for making N-((4-phenyl) methylphenyl) piperazines | SUNTORY LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |