SCHEMBL6561370

SCHEMBL6561370

Ic1ccc2c(I)cccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
PLAU P00749 3/20 0.35
F9 P00740 1/20 0.35
F10 P00742 1/20 0.35
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
NOS1 P29475 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1B1 Q16678 1/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HSD17B1 P14061 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19230461 0.83 ALDH1A1 (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9716505 0.83 ALDH1A1 (0.42) CYP1A2ALDH1A1HIF1AHSD17B10CYP1B1
SCHEMBL6562931 0.81 ALDH1A1 (0.38) CYP1A2PLAUF9F10ACHE
SCHEMBL16723362 0.79 ALDH1A1 (0.43) CYP1A2PLAUF9F10ERBB2
SCHEMBL24715117 0.77 CYP2A6 (0.48) PLAUF9F10AHRALDH1A1
SCHEMBL17993280 0.77 ALDH1A1 (0.54) CYP1A2PLAUALDH1A1HSD17B10KDM4E
SCHEMBL771906 0.77 PLAU (0.59) CYP1A2PLAUESR1ESR2KDM4E
SCHEMBL22356958 0.77 PLAU (0.59) PLAUF9F10ALDH1A1HIF1A
SCHEMBL18810167 0.77 CYP1A2 (0.63) CYP1A2PLAUERBB2FYNMAOA
SCHEMBL7837374 0.77 CYP1A2 (0.63) CYP1A2MAOAACHEALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11825740-B2 Amine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-11814395-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11818951-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11744146-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-20230172064-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-11647669-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-09 US disclosed
US-11594684-B2 Condensed-cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-28 US disclosed
US-11588120-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-11569448-B2 Cross-linkable arylamine-based compound, polymer obtained therefrom, light-emitting device including the polymer, and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-31 US disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed
EP-0556337-A1 OXYIODINATION PROCESS FOR MANUFACTURE OF 2,6-DIIODONAPHTHALENE EASTMAN KODAK COMPANY (US) 1993-08-25 EP disclosed
US-5233075-A Process for the preparation of aromatic carboxylic acid esters EASTMAN KODAK COMPANY (US) 1993-08-03 US disclosed
EP-0550671-A1 PROCESS FOR PREPARING A PRODUCT STREAM RICH IN NAPHTHALENE AND 2-MONOIODONAPHTHALENE EASTMAN KODAK COMPANY (US) 1993-07-14 EP disclosed
WO-1992007811-A1 OXYIODINATION PROCESS FOR MANUFACTURE OF 2,6-DIIODONAPHTHALENE EASTMAN KODAK COMPANY (US) 1992-05-14 WO disclosed
WO-1992004308-A1 PROCESS FOR PREPARING A PRODUCT STREAM RICH IN NAPHTHALENE AND 2-MONOIODONAPHTHALENE EASTMAN KODAK COMPANY (US) 1992-03-19 WO disclosed
US-5082982-A Zeolite type X catalyst EASTMAN KODAK COMPANY (US) 1992-01-21 US disclosed
US-5026931-A Process for preparing a product stream rich in naphthalene and 2-monoiodonaphthalene EASTMAN KODAK COMPANY (US) 1991-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647669-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 CYP1A2 14/4885PLAU 4266/4885F9 1648/4885
US-11814395-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, MCM4 CYP1A2 2378/4885PLAU 3335/4885F9 2152/4885
US-11594684-B2 Condensed-cyclic compound and organic light emitting device including the same CRY1, SMCHD1, CXCR1 CYP1A2 1983/4885PLAU 4154/4885F9 461/4885
US-20230172064-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, NQO1, CYP2E1 CYP1A2 15/4885PLAU 4078/4885F9 1263/4885
US-11588120-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 CYP1A2 857/4885PLAU 3640/4885F9 1714/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 CYP1A2 61/4885PLAU 4418/4885F9 360/4885
US-11818951-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNE2, CCNE1 CYP1A2 1326/4885PLAU 4236/4885F9 1428/4885
US-11744146-B2 Amine-based compound and organic light-emitting device including the same AOC2, AOC1, EML4 CYP1A2 456/4885PLAU 3940/4885F9 2369/4885
US-11825740-B2 Amine compound and organic light-emitting device including the same AOC2, AOC1, AOC3 CYP1A2 126/4885PLAU 4146/4885F9 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.