Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563677 | 0.85 | MRGPRX1 (0.43) | F2MRGPRX1ACACB | |
| SCHEMBL6563835 | 0.85 | MEN1 (0.52) | LTB4R2MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL6561886 | 0.82 | PLAU (0.53) | F2NPC1KMT2AMRGPRX1ACACB | |
| SCHEMBL6563625 | 0.80 | PRSS1 (0.43) | F2MRGPRX1ALDH1A1 | |
| SCHEMBL6561827 | 0.80 | MRGPRX1 (0.51) | F2MRGPRX1 | |
| SCHEMBL6565256 | 0.78 | AKR1C3 (0.44) | F2MRGPRX1ALDH1A1 | |
| SCHEMBL6563743 | 0.76 | PRSS1 (0.43) | F2ACACB | |
| SCHEMBL6563916 | 0.75 | TMPRSS6 (0.47) | F2MEN1KMT2AMRGPRX1ALDH1A1 | |
| SCHEMBL6563461 | 0.73 | PRSS1 (0.49) | F2MRGPRX1 | |
| SCHEMBL7673744 | 0.73 | ASIC3 (0.40) | F2MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |