Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565292 | 0.81 | KCNA5 (0.39) | — | |
| SCHEMBL6563255 | 0.81 | PRSS1 (0.44) | ASIC3PLAUPRSS1F2MRGPRX1 | |
| SCHEMBL6561886 | 0.80 | PLAU (0.53) | PLAUF2MRGPRX1 | |
| SCHEMBL6563677 | 0.79 | MRGPRX1 (0.43) | PRSS1F2MRGPRX1F10F7 | |
| SCHEMBL6561827 | 0.75 | MRGPRX1 (0.51) | ASIC3PRSS1F2MRGPRX1F10 | |
| SCHEMBL6563625 | 0.75 | PRSS1 (0.43) | ASIC3PRSS1F2MRGPRX1F10 | |
| SCHEMBL6563277 | 0.73 | F2 (0.41) | ASIC3PLAUPRSS1F2MRGPRX1 | |
| SCHEMBL6563734 | 0.73 | LTB4R2 (0.45) | F2MRGPRX1 | |
| SCHEMBL6563250 | 0.73 | PLAU (0.54) | PLAUPRSS1F2F10PRSS2 | |
| SCHEMBL6565690 | 0.73 | PLAU (0.54) | PLAUPRSS1F2F10PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |