Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565427 | 0.90 | VNN1 (0.46) | VNN1MEN1KMT2APGREGLN1 | |
| SCHEMBL6563532 | 0.87 | ALDH1A1 (0.44) | VNN1MEN1KMT2AEGLN1LMNA | |
| SCHEMBL7675043 | 0.87 | F7 (0.42) | VNN1PGREGLN1GRM5 | |
| SCHEMBL6565480 | 0.82 | GSK3B (0.47) | VNN1TDP1LMNA | |
| SCHEMBL6564223 | 0.79 | VNN1 (0.41) | VNN1MEN1KMT2AEGLN1LMNA | |
| SCHEMBL6563213 | 0.77 | KMT2A (0.39) | VNN1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL6563651 | 0.77 | MAPK13 (0.45) | MEN1KMT2ACYP11B1CYP11B2EGLN1 | |
| SCHEMBL6561875 | 0.76 | HPGD (0.47) | MEN1CYP2C9CYP2C19KMT2APGR | |
| SCHEMBL6565408 | 0.75 | CNR1 (0.41) | VNN1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6565441 | 0.75 | KMT2A (0.46) | VNN1MEN1KMT2AEGLN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |