Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965977 | 0.98 | ADRA2A (0.57) | ADRA2AADRA2CHTR2BDRD3HTR2A | |
| SCHEMBL5758121 | 0.87 | ADRA2C (0.61) | ADRA2AADRA2CHTR2BDRD3HTR2A | |
| SCHEMBL13305330 | 0.79 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL5154776 | 0.78 | ADRA2C (0.55) | ADRA2CALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL5758222 | 0.77 | OPRM1 (0.53) | ADRA2AADRA2CHTR2BDRD3ALDH1A1 | |
| SCHEMBL5759101 | 0.76 | HTR7 (0.56) | ADRA2AADRA2CHTR2BDRD3SIGMAR1 | |
| SCHEMBL4229105 | 0.76 | ADRA2A (0.48) | ADRA2AADRA2CHTR2BDRD3HTR2A | |
| SCHEMBL17473048 | 0.76 | NPC1 (0.57) | ADRA2CALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL30957362 | 0.76 | NPC1 (0.57) | ADRA2CALDH1A1KMT2ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7468181 | 0.76 | CCR5 (0.50) | ADRA2AADRA2CHTR2BDRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |