Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | BPTF | Q12830 | 1/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446491 | 0.82 | MBTD1 (0.55) | CYP2D6 | |
| SCHEMBL27929440 | 0.81 | FAAH (0.50) | NPC1ALDH1A1CYP3A4 | |
| SCHEMBL16081547 | 0.81 | DHFR (0.48) | ALDH1A1GFER | |
| SCHEMBL17481525 | 0.81 | TRPV6 (0.54) | NPC1ALDH1A1CCR5 | |
| SCHEMBL22324803 | 0.79 | ROCK2 (0.49) | KCNQ2MLYCDBPTFSCD5ALDH1A1 | |
| SCHEMBL1515236 | 0.78 | HTR2C (0.47) | MLYCDNPC1SCD5ALDH1A1CYP3A4 | |
| SCHEMBL29878889 | 0.78 | HTR2C (0.47) | MLYCDNPC1SCD5ALDH1A1CYP3A4 | |
| SCHEMBL10078397 | 0.78 | QDPR (0.53) | MLYCDNPC1 | |
| SCHEMBL28128323 | 0.78 | HTR1A (0.53) | MLYCDSCD5ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL17753658 | 0.77 | NPC1 (0.49) | KCNQ2MLYCDNPC1SCD5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186138-A1 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | DAIICHI SUNTORY PHARMA CO., LTD. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186138-A1 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | KCNH1, KCNH2, NPY1R | KCNQ2 89/4885MLYCD 3405/4885NPC1 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.