Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574292 | 0.87 | PGR (0.39) | PGRSLC22A12KIF11KDM1AMAOA | |
| SCHEMBL6577272 | 0.85 | PSIP1 (0.44) | PGRSLC22A12KIF11KHKAR | |
| SCHEMBL4624565 | 0.79 | TRPV4 (0.43) | PGRSLC22A12KDM1AMAOANR3C1 | |
| SCHEMBL21561086 | 0.75 | KEAP1 (0.42) | PGRSLC22A12KIF11NR3C1NR3C2 | |
| SCHEMBL1013625 | 0.74 | KIF11 (0.43) | PGRSLC22A12KIF11 | |
| SCHEMBL7679161 | 0.72 | KHK (0.35) | KHKTRPV4 | |
| SCHEMBL3779353 | 0.72 | KDM1A (0.38) | PGRSLC22A12KDM1AMAOANR3C1 | |
| SCHEMBL13660126 | 0.71 | KHK (0.48) | KHKMAOAADRB2ADRB1TRPV4 | |
| SCHEMBL6573122 | 0.71 | PGR (0.50) | PGRSLC22A12KIF11ARTRPV4 | |
| SCHEMBL8175336 | 0.71 | GRM1 (0.42) | PGRSLC22A12NR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1162403-C | Heterocyclic benzonitrile | 拜尔公司 | 2004-08-18 | — | — | CN | disclosed |
| EP-1244615-B1 | METHOD FOR PRODUCING N-SUBSTITUTED 2,4-DIAMINO-5-FLUORO BENZONITRILES AND NOVEL INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-1003718-B1 | METHOD FOR THE PRODUCTION OF N-(5-AMINO-2-CYANO-4-FLUORO-PHENYL)-SULPHONAMIDES | BAYER CROPSCIENCE AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-6545154-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-08 | — | — | US | disclosed |
| US-20030040626-A1 | Method for the production of N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides and new intermediate products | HUPPERTS ACHIM (DE) | 2003-02-27 | — | — | US | disclosed |
| US-20030017948-A1 | Method for producing n-substituted 2,4-diamino-5-fluoro benzonitriles and novel intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-23 | — | — | US | disclosed |
| EP-1244615-A1 | METHOD FOR PRODUCING N-SUBSTITUTED 2,4-DIAMINO-5-FLUORO BENZONITRILES AND NOVEL INTERMEDIATES | Bayer Aktiengesellschaft (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-0648772-B1 | 4-Cyanophenyliminoheterocycles | BAYER AG (DE) | 2002-09-04 | — | — | EP | disclosed |
| US-6395683-B1 | CHEMICAL INTERMEDIATE FOR HERBICIDES; APPLYING TO PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-0948482-B1 | METHOD FOR PRODUCING TRIFLUOROACETOACETIC ACID ANILIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-1999005098-A1 | METHOD FOR THE PRODUCTION OF N-(5-AMINO-2-CYANO-4-FLUORO-PHENYL)-SULPHONAMIDES AND NEW INTERMEDIATE PRODUCTS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
| US-5858925-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| US-5756805-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| EP-0648749-B1 | N-cyanoaryl nitrogencontaining heterocycles | BAYER AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5681794-A | HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0757673-A1 | HETEROCYCLYLBENZONITRILES | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| US-5593945-A | HERBICIDES AND CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| WO-1995029158-A1 | HETEROCYCLYLBENZONITRILES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-02 | — | — | WO | disclosed |
| EP-0648772-A1 | 4-Cyanophenylheterocycles | BAYER AG (DE) | 1995-04-19 | — | — | EP | disclosed |
| EP-0648749-A2 | N-cynanoaryl nitrogencontaining heterocycles | BAYER AG (DE) | 1995-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040626-A1 | Method for the production of N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides and new intermediate products | PFAS, SRM, NISCH | PGR 4825/4885SLC22A12 2271/4885KIF11 3088/4885 |
| US-20030017948-A1 | Method for producing n-substituted 2,4-diamino-5-fluoro benzonitriles and novel intermediates | DDT, PFAS, DAO | PGR 4770/4885SLC22A12 3579/4885KIF11 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.