Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.49 |
| ▸ | LIPC | P11150 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599090 | 0.75 | ABHD16A (0.62) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6603229 | 0.73 | ABHD16A (0.52) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL2233598 | 0.71 | ABHD16A (0.72) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6601929 | 0.71 | ABHD16A (0.50) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL15325738 | 0.71 | ACHE (0.58) | ACHEBACE1ALDH1A1GFERKMT2A | |
| SCHEMBL11620781 | 0.71 | FAAH (0.78) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6600012 | 0.70 | MGLL (0.51) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL7040759 | 0.70 | ABHD16A (0.58) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL12204742 | 0.69 | ACHE (0.59) | ACHEBACE1ALDH1A1KDM4EGFER | |
| SCHEMBL7578034 | 0.69 | ABHD16A (0.68) | ABHD16AMGLLFAAHLPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |