Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.49 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPC | P11150 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601929 | 0.76 | ABHD16A (0.50) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6599090 | 0.76 | ABHD16A (0.62) | MGLLFAAHABHD16ALPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601568 | 0.74 | LPL (0.47) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6603229 | 0.73 | ABHD16A (0.52) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL28661673 | 0.73 | BACE1 (0.51) | IDH1BACE1KDM4EALDH1A1GAA | |
| SCHEMBL11620781 | 0.72 | FAAH (0.78) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6602421 | 0.71 | MGLL (0.54) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6599576 | 0.70 | ABHD16A (0.54) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7043150 | 0.70 | MGLL (0.63) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL6551854 | 0.70 | FAAH (0.74) | MGLLFAAHABHD16ALPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |