Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 1/20 | 0.46 |
| ▸ | LIPC | P11150 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599090 | 0.77 | ABHD16A (0.62) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6600012 | 0.76 | MGLL (0.51) | ABHD16AMGLLFAAHLPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601589 | 0.75 | ABHD16A (0.47) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6603229 | 0.74 | ABHD16A (0.52) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL2233598 | 0.73 | ABHD16A (0.72) | ABHD16AMGLLFAAHLPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6599708 | 0.72 | LPL (0.46) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6599576 | 0.71 | ABHD16A (0.54) | ABHD16AMGLLFAAHLPLLIPC | |
| SCHEMBL6599976 | 0.71 | LMNA (0.56) | ABHD16AMGLLFAAHMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6601368 | 0.71 | MGLL (0.43) | ABHD16AMGLLFAAHLPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6602539 | 0.70 | MAPT (0.45) | ABHD16AMGLLFAAHLPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |