Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.54 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPC | P11150 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6601669 | 0.78 | MGLL (0.52) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7043150 | 0.75 | MGLL (0.63) | MGLLFAAHABHD16ALIPCLIPE | |
| SCHEMBL6603229 | 0.74 | ABHD16A (0.52) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL7047556 | 0.74 | MGLL (0.57) | MGLLFAAHABHD16ALPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601748 | 0.73 | FAAH (0.44) | MGLLFAAHABHD16ALPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601568 | 0.72 | LPL (0.47) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6599090 | 0.72 | ABHD16A (0.62) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6552566 | 0.72 | MGLL (1.00) | MGLLFAAHABHD16A | |
| SCHEMBL11620781 | 0.71 | FAAH (0.78) | MGLLFAAHABHD16ALPLLIPC | |
| SCHEMBL6600012 | 0.71 | MGLL (0.51) | MGLLFAAHABHD16ALPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |