Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.51 |
| ▸ | HTR6 | P50406 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916238 | 0.77 | HTR7 (0.44) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL13118688 | 0.75 | ADRB1 (0.50) | HTR7HTR1AADRB1HTR3A | |
| SCHEMBL6629665 | 0.72 | ACMSD (0.44) | HTR6CHEK1 | |
| SCHEMBL2224935 | 0.71 | ADRB1 (0.52) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL2548096 | 0.70 | HTR7 (0.51) | HTR7HTR6HTR1AHTR2AHTR5A | |
| Hydrochloric Acid SCHEMBL4574565 | 0.69 | ADRB1 (0.50) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL30022433 | 0.68 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL3759275 | 0.68 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL13234995 | 0.68 | LTA4H (0.59) | HTR1AHTR5AADRB1HTR3A | |
| SCHEMBL13087234 | 0.68 | LATS1 (0.51) | HTR6CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-B1 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | VITA LAB (ES) | 2004-08-04 | — | — | EP | disclosed |
| CN-1478088-A | Benzothiophene derivatives, process for their preparation and their use | ά��ʵ��������˾ | 2004-02-25 | — | — | CN | disclosed |
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | LABORATORIOS VITA, S.A. (ES) | 2004-02-19 | — | — | US | disclosed |
| EP-1337528-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044170-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | TPH1, HTR1A, HTR5A | HTR7 15/4885HTR6 18/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.