Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.74 |
| ▸ | HTR6 | P50406 | 1/20 | 0.74 |
| ▸ | GOT1 | P17174 | 11/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012802 | 0.86 | ADRB1 (1.00) | ADRB1HTR6GOT1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6730585 | 0.85 | ADRB1 (0.97) | ADRB1HTR6GOT1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4662618 | 0.85 | ADRB1 (0.97) | ADRB1HTR6GOT1DRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL30839757 | 0.85 | ADRB1 (0.74) | ADRB1HTR6GOT1DRD2DRD4 | |
| Tert-Butyl Formate SCHEMBL27568631 | 0.78 | HTR6 (0.71) | ADRB1HTR6GOT1DRD2DRD4 | |
| SCHEMBL2228008 | 0.77 | GOT1 (0.70) | ADRB1HTR6GOT1DRD2DRD4 | |
| SCHEMBL6686430 | 0.76 | HTR6 (0.72) | ADRB1HTR6GOT1DRD2DRD4 | |
| SCHEMBL8861994 | 0.76 | ADRB1 (0.73) | ADRB1HTR6GOT1DRD2DRD4 | |
| SCHEMBL30160211 | 0.76 | ADRB1 (0.73) | ADRB1HTR6GOT1DRD2DRD4 | |
| SCHEMBL23102103 | 0.75 | DRD2 (0.68) | ADRB1HTR6GOT1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-B1 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | VITA LAB (ES) | 2004-08-04 | — | — | EP | disclosed |
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | LABORATORIOS VITA, S.A. (ES) | 2004-02-19 | — | — | US | disclosed |
| EP-1337528-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044170-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034219-A1 | Benzothiophene derivative compounds process of preparation and use thereof | TPH1, HTR1A, HTR5A | ADRB1 82/4885HTR6 18/4885GOT1 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.