Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660962 | 0.90 | KMT2A (0.41) | TDP1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27854995 | 0.83 | ALDH1A1 (0.41) | TDP1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL660364 | 0.81 | PDCD1 (0.43) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL660917 | 0.81 | ALDH1A1 (0.40) | TDP1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL27871677 | 0.81 | ALDH1A1 (0.38) | TDP1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL298933 | 0.80 | RAB9A (0.40) | TDP1SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL27854950 | 0.78 | ADRA2C (0.35) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7805087 | 0.75 | HDAC1 (0.40) | TDP1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL286985 | 0.75 | SMN1; SMN2 (0.41) | TDP1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL287206 | 0.74 | PTGS2 (0.47) | TDP1SMN1; SMN2HPGDMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | claimed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | TDP1 1217/4885LMNA 123/4885SMN1; SMN2 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.