SCHEMBL66154

SCHEMBL66154

NC(=O)CNc1ccc([As](=O)(O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
ALDH1A1 P00352 4/20 0.59
MEN1 O00255 2/20 0.59
LMNA P02545 2/20 0.59
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.45
RAB9A P51151 1/20 0.45
TP53 P04637 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TASP1 Q9H6P5 1/20 0.44
CYP2C19 P33261 2/20 0.39
CA9 Q16790 2/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66153 0.84 KMT2A (0.42) KMT2AALDH1A1MEN1LMNACYP1A2
SCHEMBL15413903 0.83 ALDH1A1 (0.59) KMT2AALDH1A1MEN1LMNACYP1A2
Difetarsone SCHEMBL1813594 0.78 ALDH1A1 (0.61) KMT2AALDH1A1MEN1LMNACYP1A2
SCHEMBL11647073 0.76 CA1 (0.41) ALDH1A1MAPTKDM4ERAB9ASMN1; SMN2
SCHEMBL3995569 0.76 ESR1 (0.55) KMT2AALDH1A1MEN1LMNACYP1A2
SCHEMBL3659518 0.76 PEPD (0.54) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL4395547 0.75 NPC1 (0.55) KMT2AALDH1A1MEN1LMNAMAPT
Carbarsone SCHEMBL300590 0.75 ALDH1A1 (1.00) KMT2AALDH1A1MEN1LMNACYP1A2
Hydrochloric Acid SCHEMBL4804173 0.75 ESR1 (0.54) KMT2AMEN1LMNAMAPTKDM4E
SCHEMBL5518500 0.75 ALDH1A1 (0.55) KMT2AALDH1A1MEN1MAPTCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1757607-A1 N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases Molisa GmbH (DE) 2007-02-28 EP claimed
CN-1826129-A Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS INC (US) 2006-08-30 CN claimed
EP-1578434-A2 METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS Point Therapeutics, Inc. (US) 2005-09-28 EP claimed
EP-0911031-B1 Use of arsenic for preparing a medicament for the treatment of premenstrual syndrome TARELLO WALTER (IT) 2004-12-15 EP claimed
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS, INC. 2004-04-22 US claimed
WO-2004004658-A2 METHODS AND COMPOSITIONS RELATING TO ISOLEUCINE BOROPROLINE COMPOUNDS POINT THERAPEUTICS, INC. (US) 2004-01-15 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0911031-A2 Use of arsenic for preparing a medicament for the treatment of premenstrual syndrome TARELLO, Walter (IT) 1999-04-28 EP claimed
US-20260061030-A1 COMPOSITIONS AND SYNERGISTIC METHODS FOR TREATING INFECTIONS BIOAEGIS THERAPEUTICS INC. (US) 2026-03-05 US disclosed
US-20250346906-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD274/PD-L1 GENE ALNYLAM PHARMACEUTICALS INC (US) 2025-11-13 US disclosed
US-4080340-A Nitroimidazoles MERCK & CO., INC. (US) 1978-03-21 US disclosed
US-4010176-A Isoxazole substituted nitroimidazoles MERCK & CO., INC. (US) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS KMT2A 2912/4885ALDH1A1 840/4885MEN1 504/4885
US-20250346906-A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD274/PD-L1 GENE CD274, PDCD1LG2, PDCD4 KMT2A 1243/4885ALDH1A1 2685/4885MEN1 3786/4885
US-20260061030-A1 COMPOSITIONS AND SYNERGISTIC METHODS FOR TREATING INFECTIONS SLC11A2, GSDMD, C5 KMT2A 4307/4885ALDH1A1 4432/4885MEN1 2035/4885
US-20040077601-A1 Methods and compositions relating to isoleucine boroproline compounds BCAT1, BCAT2, APOB KMT2A 4134/4885ALDH1A1 2720/4885MEN1 1014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.