Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21004783 | 0.86 | SIGMAR1 (0.43) | SIGMAR1OPRM1OPRL1DPP4PSEN1 | |
| SCHEMBL416422 | 0.80 | OPRM1 (0.50) | SIGMAR1OPRM1OPRL1DPP4PSEN1 | |
| SCHEMBL19041070 | 0.79 | SIGMAR1 (0.42) | SIGMAR1OPRM1OPRL1DPP4PSEN1 | |
| SCHEMBL31248144 | 0.79 | OPRM1 (0.51) | SIGMAR1OPRM1OPRL1DPP4TMEM97 | |
| SCHEMBL15299993 | 0.78 | PSEN1 (0.47) | SIGMAR1OPRM1OPRL1DPP4PSEN1 | |
| Ethylene SCHEMBL7936439 | 0.78 | OPRM1 (0.48) | SIGMAR1OPRM1OPRL1DPP4PSEN1 | |
| SCHEMBL665165 | 0.77 | LMNA (0.45) | CTSLCTSBCTSKNPC1ALDH1A1 | |
| SCHEMBL8033788 | 0.76 | HRH1 (0.47) | CARM1PRMT6CTSLCTSBCTSK | |
| SCHEMBL6469380 | 0.76 | OPRM1 (0.59) | SIGMAR1OPRM1OPRL1DPP4TMEM97 | |
| SCHEMBL27209463 | 0.76 | SLC6A2 (0.44) | SIGMAR1OPRM1OPRL1DPP4PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368183-A1 | Macrocyclic Compounds Having ENT1 Inhibiting Activity | iTeos Belgium SA (BE) | 2024-11-07 | — | — | US | disclosed |
| EP-4413004-A1 | MACROCYCLIC COMPOUNDS HAVING ENT1 INHIBITING ACTIVITY | iTeos Belgium SA (BE) | 2024-08-14 | — | — | EP | disclosed |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| WO-2023059739-A1 | MACROCYCLIC COMPOUNDS HAVING ENT1 INHIBITING ACTIVITY | iTeos Belgium SA (US) | 2023-04-13 | — | — | WO | disclosed |
| US-11180608-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-11180608-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-11149114-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-10-19 | — | — | US | disclosed |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110151566-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305300-A1 | Method of Ring-Opening Polymerization, and Related Compositions and Articles | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305300-A1 | Method of Ring-Opening Polymerization, and Related Compositions and Articles | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
| EP-1732621-B1 | PHOSPHOLIPID AND NON-FOULING COATING COMPOSITIONS | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2009-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368183-A1 | Macrocyclic Compounds Having ENT1 Inhibiting Activity | ENTPD5, ENTPD1, ENTPD8 | SIGMAR1 4680/4885OPRM1 3691/4885OPRL1 2197/4885 |
| US-11149114-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | DCLRE1A, ODC1, MRTO4 | SIGMAR1 2182/4885OPRM1 1156/4885OPRL1 991/4885 |
| US-11180608-B2 | Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto | DCLRE1A, ODC1, MRTO4 | SIGMAR1 2182/4885OPRM1 1156/4885OPRL1 991/4885 |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | SIGMAR1 501/4885OPRM1 2219/4885OPRL1 4231/4885 |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | SIGMAR1 501/4885OPRM1 2219/4885OPRL1 4231/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | SIGMAR1 1277/4885OPRM1 1369/4885OPRL1 1958/4885 |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | SIGMAR1 4414/4885OPRM1 3237/4885OPRL1 3379/4885 |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | SIGMAR1 501/4885OPRM1 2219/4885OPRL1 4231/4885 |
| US-20110152167-A1 | BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO | SAMM50, ADRM1, UFM1 | SIGMAR1 228/4885OPRM1 71/4885OPRL1 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.