Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 17/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644521 | 0.88 | ALDH1A1 (0.40) | KIF18ASCN10AALDH1A1 | |
| SCHEMBL6645809 | 0.84 | RAB9A (0.34) | ALDH1A1 | |
| SCHEMBL6645763 | 0.84 | NPC1 (0.33) | ALDH1A1 | |
| SCHEMBL6645614 | 0.82 | SIRT1 (0.37) | KIF18ASCN10AALDH1A1 | |
| SCHEMBL6646584 | 0.80 | SCN10A (0.44) | KIF18ASCN10AALDH1A1 | |
| SCHEMBL6644731 | 0.80 | ALDH1A1 (0.45) | KIF18AALDH1A1 | |
| SCHEMBL6644724 | 0.79 | KIF18A (0.37) | KIF18ASCN10AALDH1A1 | |
| SCHEMBL6828920 | 0.78 | SORT1 (0.35) | ALDH1A1 | |
| SCHEMBL6800939 | 0.78 | GAA (0.42) | ALDH1A1 | |
| SCHEMBL6647854 | 0.78 | ALDH1A1 (0.44) | KIF18ASCN10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | KIF18A 4764/4885SCN10A 1201/4885ALDH1A1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.