Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663513 | 0.80 | HTR1A (0.41) | HTR7DRD2HTR1AHTR6HTR2A | |
| SCHEMBL6656020 | 0.79 | MAPT (0.39) | DRD2ACHEMEN1KMT2AHTR2A | |
| SCHEMBL6658483 | 0.78 | MAPT (0.45) | HRH3CHRNB4CHRNA3ACHEMEN1 | |
| SCHEMBL6660658 | 0.78 | CHRNB4 (0.43) | HTR7HTR1ACHRNB4CHRNA3MEN1 | |
| SCHEMBL6658785 | 0.78 | CHRNB4 (0.44) | HTR7HTR1AHRH3CHRNB4CHRNA3 | |
| SCHEMBL6660649 | 0.77 | KDM1A (0.39) | HTR7DRD2HTR1AHTR6SSTR4 | |
| SCHEMBL6657550 | 0.76 | HTR1A (0.40) | HTR1AMEN1KMT2A | |
| SCHEMBL6657970 | 0.76 | ACHE (0.39) | DRD2CHRNB4CHRNA3ACHEMEN1 | |
| SCHEMBL6656969 | 0.76 | SLC2A1 (0.38) | DRD2HTR1ACHRNB4CHRNA3ACHE | |
| SCHEMBL6661589 | 0.76 | LTA4H (0.41) | DRD2HRH3CHRNB4CHRNA3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |