Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.40 |
| ▸ | HTR1D | P28221 | 11/20 | 0.40 |
| ▸ | HTR1B | P28222 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660649 | 0.88 | KDM1A (0.39) | HTR1AMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6663513 | 0.85 | HTR1A (0.41) | HTR1AHTR1DHTR1BSMN1; SMN2 | |
| SCHEMBL6656020 | 0.84 | MAPT (0.39) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6656969 | 0.79 | SLC2A1 (0.38) | HTR1AMAPTSMN1; SMN2HTT | |
| SCHEMBL6660658 | 0.79 | CHRNB4 (0.43) | HTR1AKMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL6661589 | 0.78 | LTA4H (0.41) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6658785 | 0.78 | CHRNB4 (0.44) | HTR1A | |
| SCHEMBL6660137 | 0.77 | CYP2D6 (0.42) | MAPTSMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL6658483 | 0.77 | MAPT (0.45) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL6657970 | 0.76 | ACHE (0.39) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |