Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660649 | 0.86 | KDM1A (0.39) | SLC2A1METHTR1ADRD2HTR2A | |
| SCHEMBL6663513 | 0.83 | HTR1A (0.41) | METHTR1ADRD2HTR2ASMN1; SMN2 | |
| SCHEMBL6656020 | 0.82 | MAPT (0.39) | METDRD2HTR2AACHEDRD4 | |
| SCHEMBL6657550 | 0.79 | HTR1A (0.40) | HTR1AMAPTHTTSMN1; SMN2 | |
| SCHEMBL6660658 | 0.77 | CHRNB4 (0.43) | CHRNB4CHRNA3HTR1ACHRNB1CHRNB2 | |
| SCHEMBL6658483 | 0.77 | MAPT (0.45) | CHRNB4CHRNA3ACHECHRNB1CHRNB2 | |
| SCHEMBL6656071 | 0.76 | HTR7 (0.41) | CHRNB4CHRNA3HTR1ADRD2HTR2A | |
| SCHEMBL6657970 | 0.74 | ACHE (0.39) | CHRNB4CHRNA3DRD2ACHEDRD4 | |
| SCHEMBL6658785 | 0.74 | CHRNB4 (0.44) | CHRNB4CHRNA3HTR1AFAAHCHRNB1 | |
| SCHEMBL6657776 | 0.74 | MAOB (0.48) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |