Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660649 | 0.94 | KDM1A (0.39) | HTR1AMETWDR5HTR7DRD2 | |
| SCHEMBL6657550 | 0.85 | HTR1A (0.40) | HTR1AHTR1DHTR1BSMN1; SMN2 | |
| SCHEMBL6656020 | 0.85 | MAPT (0.39) | METDRD2HTR2ANPC1RAB9A | |
| SCHEMBL6656969 | 0.83 | SLC2A1 (0.38) | HTR1AMETDRD2HTR2ASMN1; SMN2 | |
| SCHEMBL6660137 | 0.83 | CYP2D6 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6656071 | 0.80 | HTR7 (0.41) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL6658483 | 0.78 | MAPT (0.45) | — | |
| SCHEMBL6660658 | 0.78 | CHRNB4 (0.43) | HTR1AHTR7SMN1; SMN2 | |
| SCHEMBL6658785 | 0.77 | CHRNB4 (0.44) | HTR1AHTR7 | |
| SCHEMBL6657970 | 0.75 | ACHE (0.39) | DRD2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |