Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663513 | 0.83 | HTR1A (0.41) | RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6660658 | 0.81 | CHRNB4 (0.43) | CYP2D6ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL6658483 | 0.81 | MAPT (0.45) | ALDH1A1LMNAMAPTHTTMAPK1 | |
| SCHEMBL6659951 | 0.80 | MAPT (0.40) | CYP2D6MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL6657970 | 0.80 | ACHE (0.39) | CYP2D6ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6658785 | 0.80 | CHRNB4 (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL6657367 | 0.80 | HTR6 (0.42) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6660649 | 0.80 | KDM1A (0.39) | ALDH1A1MAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL6661589 | 0.79 | LTA4H (0.41) | ALDH1A1MAPTRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6657190 | 0.78 | KCNH2 (0.42) | MAPTPPARGPPARDPPARACHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |