Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657367 | 0.84 | HTR6 (0.42) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6657776 | 0.82 | MAOB (0.48) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL6657970 | 0.80 | ACHE (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6657190 | 0.80 | KCNH2 (0.42) | MEN1KMT2AMAPTKCNH2 | |
| SCHEMBL6658483 | 0.79 | MAPT (0.45) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6660658 | 0.79 | CHRNB4 (0.43) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL6661589 | 0.79 | LTA4H (0.41) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL6656357 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL6659951 | 0.79 | MAPT (0.40) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL6661071 | 0.78 | HRH3 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |