Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657442 | 0.86 | MAOB (0.42) | MAPTKMT2AMEN1MAPK1MAOB | |
| SCHEMBL6657970 | 0.83 | ACHE (0.39) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL6657367 | 0.83 | HTR6 (0.42) | KMT2AMEN1 | |
| SCHEMBL6660658 | 0.82 | CHRNB4 (0.43) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL6658483 | 0.82 | MAPT (0.45) | MAPTKMT2AMEN1MAPK1TDP1 | |
| SCHEMBL6658785 | 0.81 | CHRNB4 (0.44) | FAAHCHRNB4CHRNA3 | |
| SCHEMBL6660137 | 0.80 | CYP2D6 (0.42) | MAPTCYP2D6MAPK1NPC1RAB9A | |
| SCHEMBL6661589 | 0.80 | LTA4H (0.41) | MAPTKMT2AMEN1FAAHDRD2 | |
| SCHEMBL6657190 | 0.79 | KCNH2 (0.42) | MAPTKMT2AMEN1FAAHCHRNB4 | |
| SCHEMBL6657776 | 0.79 | MAOB (0.48) | KMT2AMEN1MAOBMAOACHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |