SCHEMBL666561

SCHEMBL666561

CCCCCCCCCCC[CH]C(F)CCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
TSHR P16473 3/20 0.41
LMNA P02545 1/20 0.38
DNM1 Q05193 4/20 0.37
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH4 P08319 1/20 0.36
ADH7 P40394 1/20 0.36
THRB P10828 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274976 1.00 MAPT (0.42) MAPTTSHRLMNADNM1FAAH
SCHEMBL7206547 0.78 MEN1 (0.47) MAPTLMNAFAAHTRPV1THRB
SCHEMBL11858917 0.76 MAPT (0.45) MAPTTSHRLMNADNM1ADH1B
SCHEMBL15902252 0.76 TSHR (0.44) TSHRLMNADNM1FAAHTRPV1
SCHEMBL15902253 0.76 TSHR (0.44) TSHRLMNADNM1FAAHTRPV1
SCHEMBL2319980 0.76 MAPT (0.45) MAPTTSHRLMNADNM1ADH1B
SCHEMBL1667132 0.76 MAPT (0.50) MAPTTSHRLMNADNM1ADH1B
SCHEMBL9755655 0.76 MAPT (0.50) MAPTTSHRLMNADNM1ADH1B
SCHEMBL21196910 0.76 TSHR (0.44) TSHRLMNADNM1FAAHTRPV1
SCHEMBL31243205 0.76 MAPT (0.50) MAPTTSHRLMNADNM1ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945092-A SOLVENT AND ORGANOSILOXANE EMULSIFIER WITH HYDROPHILIC RADICAL REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-08-31 US claimed
US-20120045493-A1 Solid Cosmetic Composition with Structurant and Electrolyte Solution CITICORP USA, INC., AS COLLATERAL AGENT 2012-02-23 US disclosed
US-20100008882-A1 Silicone polyester resins in personal care applications LAVAY CARTER 2010-01-14 US disclosed
US-20090053155-A1 Cosmetic Compositions Containing Silicone/Organic Copolymer REVLON CONSUMER PRODUCTS CORPORATION (US) 2009-02-26 US disclosed
US-7407666-B2 Linear silicone resins in personal care applications SILTECH LLC (US) 2008-08-05 US disclosed
US-20080152606-A1 Compositions for Treating Keratinous Surfaces REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-06-26 US disclosed
US-20080112990-A1 Cosmetic Compositions REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-05-15 US disclosed
US-20080044367-A1 Cosmetic Compositions with Film Forming Polymer REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-02-21 US disclosed
US-20080031834-A1 Cosmetic Compositions REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-02-07 US disclosed
US-20070243220-A1 Cosmetic Compositions CITICORP USA, INC. 2007-10-18 US disclosed
US-6033651-A WATER AND OIL EMULSION COMPRISING A GELLED AQUEOUS PHASE COMPRISING A POLYSACCHARIDE GELLANT AND AN ANTIPERSPIRANT ACTIVE INGREDIENT SOLUBILIZED IN THE AQUEOUS SINGLE PHASE; AND AN OIL PHASE. REVLON CONSUMER PRODUCTS CORPORATION (US) 2000-03-07 US disclosed
WO-2000007550-A1 METHOD FOR IMPROVING THE FADE RESISTANCE OF HAIR AND RELATED COMPOSITIONS REVLON CONSUMER PRODUCTS CORPORATION (US) 2000-02-17 WO disclosed
WO-1999063951-A1 GEL COSMETIC COMPOSITIONS REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-12-16 WO disclosed
US-5989533-A Hair conditioning compositions containing alpha or beta hydroxy acid esters REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-11-23 US disclosed
WO-1999009937-A1 MOISTURIZING COSMETIC STICK COMPOSITIONS REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-03-04 WO disclosed
WO-1999009936-A1 METHOD FOR TREATING CHAPPED LIPS REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-03-04 WO disclosed
WO-1999003447-A1 HAIR CONDITIONING COMPOSITIONS CONTAINING ALPHA OR BETA HYDROXY ACID ESTERS REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-01-28 WO disclosed
US-5837223-A ANHYDROUS COMPOSITION COMPRISING VOLATILE SOLVENT, FLUORO-GUERBET ESTER, SILOXY SILICATE POLYMER, WAX, OIL, DRY PARTICULATE MATERIAL REVLON CONSUMER PRODUCTS CORPORATION (US) 1998-11-17 US disclosed
EP-0799019-A1 TRANSFER RESISTANT COSMETIC STICK COMPOSITIONS WITH SEMI-MATTE FINISH Revlon Consumer Products Corporation (US) 1997-10-08 EP disclosed
WO-1997016157-A1 TRANSFER RESISTANT COSMETIC STICK COMPOSITIONS WITH SEMI-MATTE FINISH REVLON CONSUMER PRODUCTS CORPORATION (US) 1997-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045493-A1 Solid Cosmetic Composition with Structurant and Electrolyte Solution LCT, CUTA, DLST MAPT 1634/4885TSHR 2616/4885LMNA 518/4885
US-20080031834-A1 Cosmetic Compositions DPM1, DDT, DUS2 MAPT 1429/4885TSHR 4226/4885LMNA 864/4885
US-20080044367-A1 Cosmetic Compositions with Film Forming Polymer CUTA, KRT18, DSG1 MAPT 871/4885TSHR 4513/4885LMNA 1249/4885
US-20080112990-A1 Cosmetic Compositions PLOD3, COL14A1, COL2A1 MAPT 3429/4885TSHR 1675/4885LMNA 24/4885
US-20070243220-A1 Cosmetic Compositions CUTA, PARG, PCBP1 MAPT 2507/4885TSHR 2904/4885LMNA 1097/4885
US-20100008882-A1 Silicone polyester resins in personal care applications PUF60, CUTA, FAM83A MAPT 2189/4885TSHR 2750/4885LMNA 800/4885
US-20080152606-A1 Compositions for Treating Keratinous Surfaces KRT18, PLOD3, GLA MAPT 1670/4885TSHR 1621/4885LMNA 2346/4885
US-20090053155-A1 Cosmetic Compositions Containing Silicone/Organic Copolymer LAGE3, CUTA, SMURF1 MAPT 928/4885TSHR 3542/4885LMNA 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.