Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EDNRB | P24530 | 4/20 | 0.45 |
| ▸ | EDNRA | P25101 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473746 | 0.87 | PTGS2 (0.58) | MT-CO2PTGS2TSHRMAPK1EDNRB | |
| SCHEMBL8474183 | 0.81 | ALDH1A1 (0.49) | MT-CO2PTGS2TSHRMAPK1EDNRB | |
| SCHEMBL30637685 | 0.77 | EDNRB (0.59) | TSHRMAPK1EDNRBEDNRAALDH1A1 | |
| SCHEMBL7222597 | 0.74 | EDNRB (0.61) | TSHRMAPK1EDNRBEDNRAKMT2A | |
| SCHEMBL9063934 | 0.74 | EDNRB (0.61) | TSHRMAPK1EDNRBEDNRAKMT2A | |
| SCHEMBL7228341 | 0.74 | EDNRB (0.52) | TSHRMAPK1EDNRBEDNRAKMT2A | |
| SCHEMBL9065280 | 0.74 | EDNRB (0.52) | TSHRMAPK1EDNRBEDNRAKMT2A | |
| SCHEMBL7228577 | 0.74 | EDNRB (0.61) | EDNRBEDNRAALDH1A1NPSR1 | |
| SCHEMBL8350434 | 0.74 | ALDH1A1 (0.50) | MT-CO2PTGS2TSHRMAPK1EDNRB | |
| SCHEMBL8660183 | 0.73 | CYTH2 (0.48) | TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106663-A1 | Inhibitors of fungal invasion | MICROBIA, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106663-A1 | Inhibitors of fungal invasion | ERG28, MIF, MMP17 | MT-CO2 2342/4885PTGS2 1385/4885TSHR 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.