Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL10595850 | 0.84 | TSHR (0.44) | EPHX2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL6670491 | 0.80 | EPHX2 (0.33) | EPHX2TSHRALDH1A1KDM4EMAPT | |
| Acrylamide SCHEMBL23607554 | 0.80 | TSHR (0.44) | EPHX2TSHRALDH1A1GMNNLMNA | |
| Acrylamide SCHEMBL23607567 | 0.80 | TSHR (0.44) | EPHX2TSHRALDH1A1GMNNLMNA | |
| SCHEMBL21777707 | 0.79 | EPHX2 (0.37) | EPHX2TSHRALDH1A1KDM4EMAPT | |
| Acrylic Acid Methyl Ester SCHEMBL28416168 | 0.79 | TSHR (0.39) | EPHX2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL17819150 | 0.78 | MAPT (0.50) | EPHX2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL659204 | 0.78 | — | — | |
| SCHEMBL6916916 | 0.78 | — | — | |
| Acetic Acid SCHEMBL31339251 | 0.76 | KDM4E (0.40) | EPHX2TSHRALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201720-B1 | Printing fluid additives promoting overcoat adhesion | HEWLETT PACKARD CO (US) | 2004-09-15 | — | — | EP | claimed |
| US-20220389630-A1 | METHOD FOR PRODUCING FIBER MOLDED BODY, FIBER MOLDED BODY, SOUND-ABSORBING MATERIAL, VEHICLE INTERIOR MATERIAL AND MICROFIBER | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-12-08 | — | — | US | disclosed |
| US-20220389631-A1 | FIBER MOLDED BODY FOR SOUND ABSORBING/SOUND INSULATION MATERIALS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-12-08 | — | — | US | disclosed |
| US-10982054-B2 | Polymer gel and preparation method therefor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-04-20 | — | — | US | disclosed |
| US-10858272-B2 | Barium-sulfate scale deposition inhibitor, method for inhibiting barium-sulfate scale deposition, and barium-sulfate scale deposition inhibitor composition | NIPPON SHOKUBAI CO., LTD. (JP) | 2020-12-08 | — | — | US | disclosed |
| WO-2019193849-A1 | COAGULATIVE SEPARATION DEVICE, COAGULATIVE SEPARATION METHOD, WATER QUALITY MEASUREMENT DEVICE, WATER QUALITY MEASUREMENT METHOD, COAGULATIVE SEPARATION TREATMENT SYSTEM, AND COAGULATIVE SEPARATION TREATMENT METHOD | オルガノ株式会社 | 2019-10-10 | — | — | WO | disclosed |
| US-20180265384-A1 | BARIUM-SULFATE SCALE DEPOSITION INHIBITOR, METHOD FOR INHIBITING BARIUM-SULFATE SCALE DEPOSITION, AND BARIUM-SULFATE SCALE DEPOSITION INHIBITOR COMPOSITION | NIPPON SHOKUBAI CO., LTD. (JP) | 2018-09-20 | — | — | US | disclosed |
| US-20170342220-A1 | POLYMER GEL AND PREPARATION METHOD THEREFOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-11-30 | — | — | US | disclosed |
| US-6551705-B1 | Antimicrobial fibers | MITSUBISHI RAYON CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6524508-B1 | Wet spinning polyacrylonitrile solution; immersing water-swollen acrylic fibers into acidic chitosan solution; densification, drying; washfastness | MITSUBISHI RAYON CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| US-5367018-A | Paints free of coalescing solvent formed from dispersion in water and micronizing under high shear and polymerization vinyl acetate to produce binder | THE GLIDDEN COMPANY (US) | 1994-11-22 | — | — | US | disclosed |
| US-5346948-A | Vinyl acetate matrix polymer containing chlorinated hydrocarbon modifier | THE GLIDDEN COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0611809-A2 | Latex paints with microemulsion modifier and process for their preparation | THE GLIDDEN COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| US-4855282-A | Recording material and method for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| US-4847236-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0272099-A2 | Color-forming sheet recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |