Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenyl Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.77 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.77 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.77 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL9385376 | 1.00 | HDAC1 (0.77) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL9175294 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL5351527 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL5351804 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL7736260 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL11668372 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL6534962 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL10878200 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL14715904 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Phenyl Propionic Acid SCHEMBL376109 | 0.95 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122017230-A | Immunodiagnosis reagent promoter and preparation method thereof | 北京昂领科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-119258017-A | Preparation method of enrofloxacin suspension with high stability and release rate | 山东信得科技股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-118633598-A | Orange sun-burn prevention spray protection suspension and preparation method thereof | 郑州郑氏化工产品有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-116397351-A | Antibacterial spinning oil suitable for acetate fibers for cigarette filter sticks | 苏州善进食品科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-116043368-A | Antibacterial spinning oil suitable for acetate fibers for cigarette filter sticks | 苏州善进食品科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-115975965-A | Lactate dehydrogenase and coding gene, recombinant vector, recombinant bacterium and leavening agent thereof, and application of lactate dehydrogenase and coding gene, recombinant vector, recombinant bacterium and leavening agent | 台州学院 | 2023-04-18 | — | — | CN | claimed |
| CN-115778897-A | Stable methotrexate pharmaceutical preparation and preparation method thereof | 深圳市贝美药业有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115651349-A | PC/ABS composite material and preparation method thereof, blow molding die and blow molding method | 东莞市优特美工程塑料有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115337210-A | Multiple intelligent slow-release ice film for cosmetics and preparation method thereof | 守正创新生物科技(天津)有限公司 | 2022-11-15 | — | — | CN | claimed |
| US-11390531-B2 | Mesoporous silica film structure having ultra-large pore and method of manufacturing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-07-19 | — | — | US | claimed |
| CN-112401088-A | Japanese eel adult eel feed and preparation method thereof | 福建大昌盛饲料有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-108384210-B | Application of pyruvate and modified polylactic acid | 中国科学院长春应用化学研究所 | 2020-07-28 | — | — | CN | claimed |
| CN-110812767-A | High-multiple anti-solubility aqueous film-forming foam extinguishing agent and preparation method thereof | 湖北省汉楚澳龙消防设备有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110669271-A | Gas-phase antirust film and preparation method thereof | 刘振国 | 2020-01-10 | — | — | CN | claimed |
| CN-110540610-A | (methyl) acrylate polymer and preparation method thereof | ZHEJIANG RES INST CHEMICAL IND LTD | 2019-12-06 | — | — | CN | claimed |
| US-20170056381-A1 | PYRIDOXAMINE FOR THE TREATMENT OF SICKLE CELL DISEASE, THALASSEMIA AND RELATED BLOOD DISEASES | NANOMETICS LLC (US) | 2017-03-02 | — | — | US | claimed |
| WO-2016196281-A1 | MTAP INHIBITORS FOR THE TREATMENT OF SICKLE CEMTAP DISEASE | NANOMETICS LLC (US) | 2016-12-08 | — | — | WO | claimed |
| WO-2015127163-A1 | PYRIDOXAMINE FOR THE TREATMENT OF SICKLE CELL DISEASE, THALASSEMIA AND RELATED BLOOD DISEASES | PHD BIOSCIENCES ( FORMERLY NANOMETICS LLC) (US) | 2015-08-27 | — | — | WO | claimed |
| EP-1289515-B1 | PHARMACEUTICAL COMPOSITION CONTAINING AT LEAST A POLYMER ASSOCIATED OR CONJUGATED WITH AT LEAST A PHENYLALKYLCARBOXYLIC ACID SALT, CONJUGATE POLYMERS AND USES THEREOF | BIODEX (FR) | 2004-10-13 | — | — | EP | claimed |
| US-20030171333-A1 | Pharmaceutical composition containing at least a polymer combined with or conjugated to at least a phenylalkylcarboxylic acid salt, conjugate polymers and uses thereof | BIODEX (FR) | 2003-09-11 | — | — | US | claimed |