Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TPMT | P51580 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15673397 | 0.89 | TSHR (0.65) | TSHRTPMTCA12CA1CA2 | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL716891 | 0.88 | KDM4E (0.63) | TSHRTPMTCA12CA1CA2 | |
| SCHEMBL1928259 | 0.86 | LMNA (0.62) | TSHRTPMTGAAALDH1A1TUBB4A | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL10620428 | 0.86 | KDM4E (0.61) | TSHRTPMTCA12CA1CA2 | |
| 3,4,5-Triacetoxybenzoic Acid SCHEMBL9491767 | 0.86 | KDM4E (0.61) | TSHRTPMTCA12CA1CA2 | |
| SCHEMBL5807605 | 0.85 | TSHR (0.64) | TSHRTPMTCA12CA1CA2 | |
| SCHEMBL9252598 | 0.84 | TSHR (0.51) | TSHRTPMTCA12CA1CA2 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 | 0.84 | TPMT (0.78) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL23467799 | 0.83 | TUBB1 (0.50) | TSHRTPMTGAAALDH1A1TUBB4A | |
| SCHEMBL668245 | 0.83 | TUBB4A (0.50) | TSHRTPMTGAAALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368032-B | Phenolic acid derivative compound and application thereof | 大峰LS株式会社 | 2021-06-08 | — | — | CN | disclosed |
| US-10696623-B2 | Phenolic acid derivative compound and use thereof | DAEBONG LS, LTD (KR) | 2020-06-30 | — | — | US | disclosed |
| US-10611727-B2 | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives | UNIVERSITAT DE BARCELONA (ES) | 2020-04-07 | — | — | US | disclosed |
| US-10611727-B2 | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives | UNIVERSITAT DE BARCELONA (ES) | 2020-04-07 | — | — | US | disclosed |
| US-20190084927-A1 | 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2019-03-21 | — | — | US | disclosed |
| US-20190084927-A1 | 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES | UNIVERSITAT DE BARCELONA (ES) | 2019-03-21 | — | — | US | disclosed |
| US-20180362448-A1 | NOVEL PHENOLIC ACID DERIVATIVE COMPOUND AND USE THEREOF | DAEBONG LS, LTD (KR) | 2018-12-20 | — | — | US | disclosed |
| US-10125097-B2 | 1- [1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives | UNIVERSITAT DE BARCELONA (ES) | 2018-11-13 | — | — | US | disclosed |
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| WO-2000012508-A2 | PYRROLBENZODIAZEPINES | SPIROGEN LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |
| US-5559109-A | Method of treating a PAF-mediated pathology or for treating or preventing psoriasis, nephritis, asthma or shock by administering a PAF antagonist | SANKKO COMPANY, LIMITED (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5556852-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0421456-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5223513-A | Anticholesterol agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5192766-A | Platelet activating factor antagonist | SANKYO COMPANY, LIMITED (JP) | 1993-03-09 | — | — | US | disclosed |
| EP-0421456-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4574066-A | MELT POLYMERIZATION CATALYZED BY POTASSIUM ACETATE | CELANESE CORPORATION (US) | 1986-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084927-A1 | 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES | BDNF, GRIN1, NLN | TSHR 4378/4885TPMT 282/4885CA12 2479/4885 |
| US-10696623-B2 | Phenolic acid derivative compound and use thereof | TYR, COMT, PAH | TSHR 4774/4885TPMT 2750/4885CA12 2562/4885 |
| US-10611727-B2 | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives | BDNF, GRIN1, NLN | TSHR 4378/4885TPMT 282/4885CA12 2479/4885 |
| US-10125097-B2 | 1- [1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives | BDNF, GRIN2A, NLN | TSHR 4390/4885TPMT 200/4885CA12 2329/4885 |
| US-20180362448-A1 | NOVEL PHENOLIC ACID DERIVATIVE COMPOUND AND USE THEREOF | TYR, LPO, TH | TSHR 4811/4885TPMT 2970/4885CA12 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.