Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687780 | 0.93 | PARP1 (0.46) | HPGDCNR2PARP1TSHRMEN1 | |
| SCHEMBL6690537 | 0.89 | HPGD (0.48) | HPGDCNR2HRH3PARP1TSHR | |
| SCHEMBL6687439 | 0.86 | HPGD (0.46) | HPGDCNR2HRH3PARP1TSHR | |
| SCHEMBL6692407 | 0.86 | KMT2A (0.54) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3226312 | 0.83 | ALDH1A1 (0.48) | HPGDTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6703688 | 0.83 | PARP1 (0.49) | HPGDCNR2PARP1TSHRMEN1 | |
| SCHEMBL6688446 | 0.82 | PARP1 (0.46) | HPGDCNR2HRH3PARP1TSHR | |
| SCHEMBL6692575 | 0.81 | LMNA (0.45) | HPGDCNR2PARP1TSHRKMT2A | |
| SCHEMBL6692232 | 0.80 | KMT2A (0.49) | HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11938971 | 0.79 | DRD2 (0.54) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |