Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382591 | 0.87 | HTR6 (0.38) | TLR9GAASMN1; SMN2HTTCA12 | |
| SCHEMBL9142537 | 0.83 | TLR9 (0.39) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL11150598 | 0.81 | C5AR1 (0.41) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL30923444 | 0.81 | TERT (0.37) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL1982598 | 0.80 | TERT (0.49) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL4462187 | 0.80 | ALDH1A1 (0.44) | TLR9GAASMN1; SMN2LMNAHTT | |
| Benzene SCHEMBL29261851 | 0.79 | GAA (0.56) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL10913095 | 0.79 | GAA (0.43) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL9131821 | 0.79 | GAA (0.43) | TLR9GAASMN1; SMN2LMNAHTT | |
| SCHEMBL1254755 | 0.79 | GAA (0.43) | TLR9GAASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | claimed |
| CN-119968229-A | Filter with electrostatic filtering function | 马蒂夫卢森堡公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-109312178-A | The method for manufacturing food, cosmetics and drug packages | 爱克发有限公司 | 2019-02-05 | — | — | CN | disclosed |
| US-10131908-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-11-20 | — | — | US | disclosed |
| US-9278949-B2 | Polymerizable thioxanthones | AGFA GRAPHICS NV (BE) | 2016-03-08 | — | — | US | disclosed |
| US-20150158839-A1 | POLYMERIZABLE THIOXANTHONES | AGFA NV (BE) | 2015-06-11 | — | — | US | disclosed |
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | BANK OF AMERICA, N.A. | 2015-03-19 | — | — | US | disclosed |
| US-8927513-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8883873-B2 | Polymerizable polymeric photoinitiators and radiation curable compositions | AGFA GRAPHICS NV (BE) | 2014-11-11 | — | — | US | disclosed |
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120046376-A1 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-02-23 | — | — | US | disclosed |
| WO-2011005860-A2 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| US-7144993-B2 | Process for the preparation of 4-methyl-7-aminoquinolones | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-12-05 | — | — | US | disclosed |
| US-20050222397-A1 | Process for the preparation of 4-methyl-7-aminoquinolones | CIBA SPECIALTY CHEMICALS CORP. | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | NSUN2, RNGTT, RNMT | TLR9 2432/4885GAA 1216/4885SMN1; SMN2 2144/4885 |
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | NSUN2, RNGTT, RNMT | TLR9 2437/4885GAA 1215/4885SMN1; SMN2 2114/4885 |
| US-20050222397-A1 | Process for the preparation of 4-methyl-7-aminoquinolones | CBR1, CBR3, MRPL21 | TLR9 3205/4885GAA 3977/4885SMN1; SMN2 3992/4885 |
| US-10131908-B2 | 5′ phosphate mimics | NSUN2, RNGTT, RNMT | TLR9 2344/4885GAA 1221/4885SMN1; SMN2 2102/4885 |
| US-20150158839-A1 | POLYMERIZABLE THIOXANTHONES | HADHA, TST, ASS1 | TLR9 2409/4885GAA 3820/4885SMN1; SMN2 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.