SCHEMBL6702137

SCHEMBL6702137

CC(=O)O[Si](OC(C)=O)(c1ccccc1)C(C)N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 3/20 0.35
PTGS1 P23219 2/20 0.35
ALPI P09923 1/20 0.35
PKM P14618 1/20 0.35
XIAP P98170 1/20 0.35
SLC7A5 Q01650 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2C P18825 1/20 0.33
ELANE P08246 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703027 0.85 MTNR1A (0.38) ALOX5MTNR1AMTNR1BCES2CES1
SCHEMBL704933 0.76 CES2 (0.39) ALOX5MTNR1AMTNR1BCES2CES1
SCHEMBL705831 0.75 TSHR (0.32) MTNR1AMTNR1BHPGDTSHRLMNA
SCHEMBL6695799 0.75 MAOA (0.36) ALDH1A1ADRA2AADRA2CTAAR1KDM4E
SCHEMBL11762327 0.75 ALDH1A1 (0.36) MTNR1AMTNR1BCES2CES1ALDH1A1
SCHEMBL705565 0.74 MTNR1A (0.38) ALOX5MTNR1AMTNR1BCES2CES1
SCHEMBL132756 0.72 CES2 (0.43) MTNR1AMTNR1BCES2CES1ALDH1A1
SCHEMBL132933 0.72 CES2 (0.43) MTNR1AMTNR1BCES2CES1ALDH1A1
SCHEMBL476126 0.72 CES2 (0.43) ALOX5MTNR1AMTNR1BCES2CES1
SCHEMBL27869554 0.72 CES2 (0.39) ALOX5MTNR1AMTNR1BCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed