Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542798 | 0.78 | RAB9A (0.54) | RAB9AKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL28004668 | 0.74 | CNR2 (0.47) | CNR2ALDH1A1CCR2POLBCYP1A2 | |
| SCHEMBL28112083 | 0.74 | CNR2 (0.68) | CNR2MCL1ALDH1A1CCR2POLB | |
| SCHEMBL15649683 | 0.73 | CCR2 (0.58) | CNR2MCL1CCR2 | |
| SCHEMBL6703577 | 0.73 | HSD17B10 (0.48) | KDM4EALDH1A1CCR2HSD17B10 | |
| SCHEMBL19687591 | 0.69 | MEN1 (0.43) | RAB9AKDM4EESR1ESR2 | |
| SCHEMBL8417551 | 0.68 | FABP4 (0.56) | MCL1KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL4024245 | 0.67 | FABP4 (0.50) | KDM4EALDH1A1HSD17B10GLAHPGD | |
| SCHEMBL19687581 | 0.66 | KDM4E (0.44) | RAB9AKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6703370 | 0.65 | F10 (0.51) | ALDH1A1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | disclosed |
| EP-0984960-B1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI SYNTHELABO (FR) | 2003-02-05 | — | — | EP | disclosed |
| CN-1263528-A | N-triazolyl-2-indolecarboxamides and their use in CCK-A agonists | SANOFI SYNTHELABO (FR) | 2000-08-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | RAB9A 1127/4885CNR2 73/4885SYK 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.