Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710319 | 0.90 | CHRNB2 (0.43) | NHERF1PYGLPLCG2HTT | |
| SCHEMBL6707650 | 0.90 | P2RX1 (0.39) | KMT2ARAB9ANPC1TP53LMNA | |
| SCHEMBL6713754 | 0.89 | SERPINE1 (0.43) | KCNMA1NHERF1KDRPLCG2GAA | |
| SCHEMBL6711906 | 0.89 | NHERF1 (0.46) | NHERF1PYGLPLCG2RAB9ANPC1 | |
| SCHEMBL6711851 | 0.88 | PTGES (0.40) | NHERF1PLCG2PLA2G7MEN1KMT2A | |
| SCHEMBL6710112 | 0.88 | MAP3K5 (0.45) | NHERF1PYGLPLCG2RAB9ANPC1 | |
| SCHEMBL6708889 | 0.87 | NR1H4 (0.38) | PLA2G7MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6710125 | 0.87 | SERPINE1 (0.48) | NHERF1PLCG2MEN1KMT2ARAB9A | |
| SCHEMBL6707792 | 0.86 | NHERF1 (0.40) | NHERF1LMNAHTT | |
| SCHEMBL6708019 | 0.86 | GPR35 (0.44) | NHERF1KDRPLCG2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | KCNMA1 2744/4885NHERF1 1641/4885KDR 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.