Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684518 | 0.71 | ILK (0.50) | KDM4EALDH1A1HSD17B10EPHX2ILK | |
| SCHEMBL17424258 | 0.69 | LTA4H (0.42) | KDM4EALDH1A1NPC1POLBCYP1A2 | |
| SCHEMBL18039136 | 0.68 | MAPK1 (0.52) | KDM4EALDH1A1HSD17B10ILKNPC1 | |
| SCHEMBL13707366 | 0.66 | ADORA2A (0.49) | KDM4EALDH1A1HSD17B10EPHX2NPC1 | |
| SCHEMBL8975540 | 0.66 | PIK3CD (0.60) | KDR | |
| SCHEMBL1849836 | 0.65 | POLB (0.44) | KDM4EALDH1A1HSD17B10EPHX2NPC1 | |
| SCHEMBL22977618 | 0.64 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10EPHX2NPC1 | |
| SCHEMBL978698 | 0.64 | DHFR (0.56) | KDM4EALDH1A1HSD17B10EPHX2NPC1 | |
| SCHEMBL1665919 | 0.64 | ADORA3 (0.62) | ALDH1A1HSD17B10NPC1POLBCYP1A2 | |
| SCHEMBL13312259 | 0.64 | NPC1 (0.47) | KDM4EALDH1A1HSD17B10EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109551-A4 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECH INC (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20020032325-A1 | 4-amino-3-mercapto-1,2,4-triazoles | HEINDEL NED D (US) | 2002-03-14 | — | — | US | disclosed |
| EP-1109551-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | Competitive Technologies, Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000010564-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECHNOLOGIES, INC. (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032325-A1 | 4-amino-3-mercapto-1,2,4-triazoles | TH, MAT1A, NAT1 | KDM4E 729/4885ALDH1A1 97/4885HSD17B10 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.